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2017

338. O'Leary, T.P., Shin, S., Fertan, E., Dingle, R.N., Almuklass, A., Gunn, R.K., Yu, Z., Wang, J., and Brown, R.E. Reduced acoustic startle response and peripheral hearing loss in the 5XFAD mouse model of Alzheimer’s disease Genes Brain and Behaviour, 2017, 16, 554-563. [IF = 3.743]

339. Zhang Y, Jiao G, Song C*, Gu S, Brown RE, Zhang J, Zhang P, Gagnon J, Zhang Y, Lu H. 2017. An extract from shrimp processing by-products protects SH-SY5Y cells from neurotoxicity induced by Aβ25-35. Marine Drugs, 2017, 15, 83; doi:10.3390/md15030083

340. Brown, RE. Ragged children and ragged schools. Canadian Holmes, 40 (2), 2017, 13-18. 341. Brown, RE and Bolivar, S. The importance of behavioural bioassays in neuroscience. Journal of Neuroscience Methods, 2018, 300, 68-76. http://dx.doi.org/10.1016/j.jneumeth.2017.05.022. DOI: 10.1016/j.jneumeth.2017.05.022 [IF = 2.554]

342. Brown, RE. Donald O. Hebb. In the Encyclopedia of Animal Cognition and Behavior, edited by Jennifer Vonk and Todd K. Shackelford, Springer International Publishing AG. 2017. 4 pages. Page proofs received 26 July 2017.

343. Brown, RE, Molnar, Z, Filaretova, L, Ostrovskiy, MA, Piccolino, M, Lorusso, L. The 100th anniversary of the Russian Pavlov Physiological Society. Physiology, 2017, 32, 402-407. PMID: 28978630

344. O’Leary, T.P., Robertson, A., Chipman, P. H., Rafuse, V.F. and Brown, R.E. MotorÌýfunction deficits in the 12 month-old 5xFAD mouse model of Alzheimer’s disease. Behavioural Brain Research, 2018, 337, 256–263. DOI: 10.1016/j.bbr.2017.09.009

345. Brown, RE and Wheeler, RV. The influence of Donald O. Hebb on the founders of the ISDP. Developmental Psychobiology, 2018, 60(S1), pages S12-S13. [Abstract]

346. Wheeler, RV and Brown, RE. 50 years later: The founders of the ISDP. DevelopmentalPsychobiology, 2018, 60(S1), pages S74-S75. [Abstract]

347. Brown, RE, Fertan E, and Faustova N. A Brain Museum Tour of Europe. Society for Neuroscience meeting, Washington, DC, 10-15 Nov 2017. (Poster). Program No. 021.09SA/VV22. 2017 Neuroscience Meeting Planner. Society for Neuroscience. Online. [Abstract]

348. O’Leary TP, Wang J, Brown RE. Reduced acoustic startle response and peripheral hearingÌýloss in the 5xFAD mouse model of Alzheimer’s disease. Society for Neuroscience meeting, Washington, DC, 10-15 Nov 2017. Program No. 489.1/BB17. 2017 Neuroscience Meeting Planner. Society for Neuroscience. Online. [Abstract]

2018

349. Brown, RE, Shin, S. Woodland, N. and Rae, E.A. Genotype and sex differences in longevity in transgenic mouse models of Alzheimer's disease. Chapter 42 in Ram, J.L. and Conn, P.M. (editors). Conn's Handbook of Models for Human Aging, second edition. Academic Press/Elsevier. pages 563-576.

350. King, J.L., Wong, AA, and Brown, RE. Age-related changes in the spatial frequency threshold of male and female 3xTg-AD mice using OptoMotry. Journal of Alzheimer's Disease, 2018, 62, 591-596. [IF = 3.731]

351. Zhang YP, Brown RE, Zhang PC, Zhao YT, Ju XH, Song C. DHA, EPA and their combination at various ratios differently modulated Aβ25-35-induced neurotoxicity in SH-SY5Y cells. Prostaglandins Leukotrienes, and Essential Fatty Acids, 2018, 136: 85-94. doi: 10.1016/j.plefa.2017.07.003. [IF = 2.653]

352. Brown RE, Garvock-de Montbrun T. Why did Darwin drop out of medical school? Hektoen International: A Journal of Medical Humanities, Winter 2018. Published on-line, 16 March 2018. [http://hekint.org/2018/03/15/darwin-drop-medical-school/].

353. Brown, RE. A toast to Sherlock Holmes: A man of refined tastes. Canadian Holmes, Summer 2018, pages 35-37. Published 20 May 2018.

354. Kane AE, Shin S, Wong AA, Fertan E, Faustova, N., Howlett, SE, and Brown RE.Ìý Sex differences in healthspan predict lifespan in the 3x Tg-AD mouse model of Alzheimer's Disease.Ìý Frontiers in Aging Neuroscience, June 2018, Volume 10, Article 172, 10 pages. https://doi.org/10.3389/fnagi.2018.00172

355. O'Leary, T.P., Hussin, A. T. Gunn, R.K. and Brown, R.E. Locomotor activity, emotionality, sensori-motor gating and learning and memory in the APPswe/PS1dE9 mouse model of Alzheimer’s disease. Brain Research Bulletin, 2018, 140, 347-354.

356. Liu, L., Xuan, C., Shen, P., He, T., Chang, Y., Shi, L., Tao, S., Yu, Z., Brown, R.E., and Wang, J. Hippocampal mechanisms underlying impairment in spatial learning long after establishment of noise-induced hearing loss in CBA mice. Frontiers in Systems Neuroscience,Ìý July 2018, Volume 12, Article 35, published: 24 July 2018.Ìý Ìýdoi:10.3389/fnsys.2018.00035

357. Lorusso L, Piccolino M, Motta S, Gasparello A, Barbara JG, Bossi-Régnier L, Shepherd GM, Swanson L, Magistretti P, Everitt B, Molnár Z, Brown R. Neuroscience without borders: Preserving the history of Neuroscience. European Journal of Neuroscience.Ìý2018, 48: 2099–2109. doi: 10.1111/ejn.14101.

358. Garvock-de Montbrun, T., Fertan, E., Stover, K. and Brown, RE. Motor deficits in 16-month-old male and female 3xTg-AD mice. Behavioural Brain Research, 2019, 356, 305-313. doi: 10.1016/j.bbr.2018.09.006.

359. Langille, JJ. and Brown, RE. The synaptic theory of memory: A historical survey and reconciliation of recent opposition. Frontiers in Systems Neuroscience 2018, 12: 52. doi:10.3389/fnsys.2018.00052

360.Ìý Grant, R., Wong, A.A., Fertan, E., and Brown, R.E. Whisker exploration behaviours in the 5xFAD mouse are affected by sex and retinal degeneration. Genes, Brain and Behaviour, 2018, e12532. 12 pages. https://doi.org/10.1111/gbb.12532. [Epub ahead of print].

361. O’Leary, T. P., Mantolino, H.M., Stover, K. and Brown R. E. Age-related deterioration of motor function in male and female 5xFAD mice from 3-16 months of age. Genes, Brain and Behaviour, 2018 Nov 13:e12538. doi: 10.1111/gbb.12538. [Epub ahead of print]

362. Gür E, Fertan E, Kosel F, Wong AA, Balci F & Brown RE. Sex differences in the timing behavior performance of 3xTg-AD and wild-type mice in the peak interval procedure. Behavioural Brain Research, 2019, 360: 235-243. doi: 10.1016/j.bbr.2018.11.047.

2019

363. Gür E, Fertan E, Alkins K, Wong AA, Brown RE & Balci F. Interval timing is disrupted in female 5xFAD mice: An indication of altered memory processes. Journal of Neuroscience Research, 2019; 97: 817-827. doi: 10.1002/jnr.24418.

364. Fertan E, Rodrigues GJ, Wheeler RV, Goguen D, Wong AA, James H, Stadnyk A, Brown RE, and Weaver ICG. Cognitive decline, cerebral-spleen tryptophan metabolism, oxidative stress, cytokine production, and regulation of the Txnip gene in a triple transgenic mouse model of Alzheimer disease. The American Journal of Pathology, 2019, 189 (7): 1435-1450. doi: 10.1016/j.ajpath.2019.03.006.

365. Brown RE. Why study the history of neuroscience? Frontiers in Behavioral Neuroscience 2019. 13:82. 16 pages. doi: 10.3389/fnbeh.2019.00082

366. Fertan E, Wong AA, Vienneau NA, and Brown RE. Age and sex differences in motivation and spatial working memory in 3xTg-AD mice in the Hebb-Williams maze. Behavioural Brain Research, 2019 Sep 16;370:111937 doi:10.1016/j.bbr.2019.111937.

367. Fertan E, Stover KRJ, Brant MG, Stafford PM, Kelly B, Diez-Cecilia E, Wong AA, Weaver DF and Brown RE. Effects of the novel IDO inhibitor DWG-1036 on the behavior of male and female 3xTg-AD mice. Frontiers in Pharmacology 2019, 10:1044. (published: 24 September 2019 ) doi: 10.3389/fphar.2019.01044.

368. (200) Cooke MB, O’Leary TP, Harris P, Brown RE, Snyder JS. Pathfinder: open sourceÌýsoftware for analyzing spatial navigation search strategies [version 1; peer review: awaiting peer review] F1000 Research 2019, 8:1521. First published: 28 Aug 2019. (https://doi.org/10.12688/ f1000research.20352.1)

369. Brown, R.E. Review of: Franz Joseph Gall: Naturalist of the mind, visionary of the brain byÌýStanley Finger and Paul Eling. History of Psychology, 22(4), Nov, 2019, 374-379.

2020

370. Simanaviciute U, Ahmed J, Brown RE, Connor-Robson N, Farr TD, Fertan E, Gambles, N., Garland, H., Morton, A.J.,Ìý Staiger, J.F., Skillings, E.A., Trueman, R.C.,Ìý Wade-Martins, R.,Wood, N.I., Wong, A.A.,Ìý and Grant, R.A.Ìý ÌýRecommendations for measuring whisker movements and locomotion in mice with sensory, motor, and cognitive deficits.Ìý ÌýJournal of Neuroscience Methods,Ìý 2020, 331: 108532. 13 pages. Available on-line 12 December 2019. https://doi.org/10.1016/j.jneumeth.2019.108532

371. Brown, RE.Ìý Donald O. Hebb and the Organization of Behavior: 17 years in the writing. Molecular Brain, 2020, 13: 55.Ìý 28 pages.Ìý https://doi.org/10.1186/s13041-020-00567-8

372. O’Leary, T. P., Stover, K., Mantolino, H.M., Darvesh, S., and Brown R. E. Olfactory memory from 3 to 15 months of age in the 5xFAD mouse model of Alzheimer disease.Ìý Behavioural Brain Research, 2020, 393: 112731.Ìý doi.org/10.1016/j.bbr.2020.112731.

373. Luke M, Brown RE, Rutishauser U, and Clarke DB. Polysialylated – neural cell adhesion molecule (PSA-NCAM) promotes recovery of vision after the critical period.Ìý Molecular and Cellular Neuroscience, 2020, 107, 103537.

374. Brown, R. Rejuvenation therapy: Historical background to The Creeping Man.Ìý Canadian Holmes, 43 (4) Fall 2020, pages 2-11. [Includes 374A: Brown, Richard. Author's note on Rejuvenation therapy: Historical background to The Creeping Man.Ìý Canadian Holmes, Fall 2020, pages 11-12.]

375. Fertan E, Wong AA, Purdon MK, Weaver ICCG, and Brown RE.Ìý The Effect of Background Strain on the Behavioural Phenotypes of the MDGA2+/- Mouse Model of Autism Spectrum Disorder. Genes Brain and Behaviour, 2021; 20: e12696. 18 pages.

376. Naureen Z, Beccari T, Marks R,Ìý Brown RE, Lorusso L, Pheby D, Miertus S, Herbst KL, Stuppia L, Henehan G, Falsini B, Sikora P, Lumer L, Bertelli M, and the International Bioethical Study Group. Ethics committees for the clinical experimentation at the international level with a focus on Italy.Ìý Acta Biomed 2020, 91, Supplement 13: e2020016. 15 pages.Ìý DOI: 10.23750/abm.v91i13-S.10643.

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