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The goal of 's group is to unveil the design rules underlying studies the unique mechanical properties of protein assemblies, cells, and tissues in the context of human diseases such as muscular dystrophies. The group's main techniques are atomic force microscopy, electron microscopy, X-ray scattering, and Raman spectroscopy.

Research in 's lab group involves developing microtechnology devices to measurement cell biophysical properties for asthma research. The Maksym group also does research using magnetic resonance imaging (MRI) of the lung and functional modelling of respiratory mechanics in disease, as well as medical device research and development for respiratory health diagnosis and monitoring.

's research group investigates the biological structures of bacteria, which are self-assembled and dynamic. This are of research is a rich field at the overlap of molecular biology and condensed-matter physics.

Dr. Rutenberg's broader interest is in non-equilibrium structure formation; more specifically, he finds bacteria interesting as they have a mature nanotechnology. Dr. Rutenberg's group explores how bacteria's subcellular mechanisms function despite the large noise inherent in their small size. The group models spatial and temporal patterns within bacteria, using the techniques of statistical, computational, and theoretical physics.